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Fig. 2. Averaged time courses of the changes in cGMP and IP3 contents of sea urchin eggs, compared with [Ca2+]i, after insemination. (A-C) A. crassispina and (D-F) H. pulcherrimus. cGMP (A,D) and IP3 (B,E) values are averages from three independent experiments. Error bars represent s.d. Arrows indicate the onset of fertilization potential.