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Fig. 6. Msx1 misexpression promotes AER formation. (A-D) Msx1 misexpression induces ectopic AER formation in dorsal ectoderm as detected by ectopic Fgf8 expression (arrows in A-C) and ectopic outgrowths (arrows in C, D). (A,B) Stage 24, dorsal view, (C) stage 27, dorsal towards the left, and (D) stage 30, dorsal view. Inset indicates outgrowth occurs from the dorsal aspect of the limb, the broken line highlights the AER. d and v indicate dorsal and ventral sides, respectively.