Fig. 8. One possible model to explain the phenotypes observed with hlh-8 homozygous and heterozygous mutants. Red oval with protruding square, wild-type CeTwist. Orange oval with protruding triangle, mutant CeTwist E29K. Blue oval, CeTwist partner protein that could be CeE/DA and/or an unknown protein. Gray lines represent dsDNA from the promoter of a target gene (e.g. egl-15) and green arrows represent transcription proceeding from the egl-15::gfp promoter and other SM patterning and differentiation targets. For details of each panel, see Discussion.