Fig. 4. Dwarfism and abnormal skull shape in homozygous Fgfr2IIIc mutants. (A) Live P14 wt and mutant mice. (B) Alizarin Red skeletal staining of P14 wild-type and mutant mice, showing overall small size, rounded skull, lower incisor overgrowth and shorter facial area in the mutant. (C) Growth curves demonstrating 40-50% growth retardation in the mutant.