Fig. 9. Decreased Spp1 expression in the skull and in the tibial growth plate of the Fgfr2IIIc mutant: bright-field views of radioactive in situ hybridization. (A-D) Parasagittal sections of the E18.5 head; Cand D are higher magnification of A and B, respectively. (E,F) P14 tibia. bo, basioccipital; bs, basisphenoid; pit, pituitary; ps, presphenoid bone. Scale bar: 1 mm.