Fig. 5. Morphological differences during stomach development between wild type (A,C,E,G,I) and Hoxa5/ mutants (B,D,F,H,J). Arrows delineate the prospective squamous (forestomach) and glandular (hindstomach) portions of the stomach. At E13.5 (A-D), a slight disorganization in the gastric submucosa was observed in mutants. By E15.5 (E,F), the reduced cellular density of Hoxa5/ mesenchymal layer became obvious, as shown also for E17.5 (G,H). At E17.5, formation of foldings initiated properly but they were reduced in length at birth (I,J). f, forestomach; h, hindstomach. Scale bars: 100 µm.