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Fig. 6. An Akap200 mutation dominantly suppresses the Src64B ring canal size phenotype. (A-D) Confocal projection of egg chambers stained with phosphotyrosine antibodies. (A) Wild-type stage-ten egg chamber. (B) Src64BPI/Src64BPI stage-ten egg chamber. Note small ring canals and misshapen ring canal remnant in the fused, binucleate nurse cell (arrow). (C) Akap200k07118/+; Src64BPI/Src64BPI stage-ten egg chamber. The ring canals are near wild-type-sized. (D) Akap200k07118/Akap200k07118; Src64BPI/+ stage-ten egg chamber. Ring canals are near normal sized; a ring canal remnant is indicated with an arrowhead. (E) Src64BPI/Src64BPI early stage-ten egg chamber stained with Akap200 antiserum. Except for the small ring canals, Akap200 localization in these mutants appears normal.