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Fig. 6. Downregulation of Msx1 expression. In situ hybridization shows that Msx1 was expressed in the developing ciliary epithelium (CE) at E18 (A) and P1 (B), but at a reduced level by P7 (C). In CPV2-Noggin transgenic mice, Msx1 expression was significantly downregulated in E18 (D), P1 (E) and P7 (F) eyes. Scale bars: 100 µm.