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Fig. 5. The involuted ADME of stage 10.5 embryo acts on stage 10.5 DE to elicit proper Xemx1 expression at stage 22/23. (A) DE (violet) and involuted ADME (green) were explanted and recombined at stage 10.5 (upper scheme), grown to stage 22/23 and assayed for Xemx1 expression. (B) DE and the underlying involuted ADME (red) were explanted together at stage 10.5 (lower scheme), grown to stage 22/23 and assayed for Xemx1 expression.