Fig. 3. Life span of F1 progeny produced by P0 C. elegans worms microinjected with double-stranded RNA of wrn-1. The life span of wrn-1(RNAi) worms was reduced by 2.6 (P<0.001) days compared with wild-type N2 strain at 25°C. wrn(RNAi), 11.0±0.2 (s.e.m.) days; N2(control), 13.6±0.1 days. Over 100 F1 worms were used per single data point, and each experiment was repeated three times.