Fig. 6. The activity of both Her5 and Him is necessary to prevent neurogenesis in the lateral IZ. Dorsal views of flat-mounted -8.4ngn1::egfp transgenic embryos (Blader et al., 2003) probed at the three-somite stage for egfp expression (blue) after injection of 1 mM her5MO^ATG + 0.25 mM himGripNA^ATG (A), 1 mM her5MO^ATG (B), 0.25 mM himGripNA^ATG (C), compared to an uninjected control (D). A' and D' are enlargements of the boxed areas in A and D, respectively. The IZ is indicated by pax2.1 expression (red staining). Note that the LIZ is undergoing ectopic neurogenesis only in the embryo injected with both her5MO^ATG and himGripNA^ATG (blue arrows).