Fig. 1. Overexpression of Drosophila PAT-related transporters induces overgrowth in the differentiating eye. GMR-GAL4 was used to overexpress transgenes in differentiating cells of the fly eye (B-J,L,M). Compared with controls (A,K), much greater overgrowth was induced by path^GS13857 (C,E,L), CG1139^GS10666 (D,F,M) and UAS-CG1139 (H), than by slif (B). Tor had no obvious effect on growth by itself (G), but enhanced the overgrowth phenotype induced by either path^GS13857 (I) or CG1139^GS10666 (J). Where the ommatidial array was not disorganised, relative ommatidial size was measured (bottom of panel: mean±s.d.; ^*P<0.01; ^**P<0.001). Eyes bulged from the head in more extreme cases of overgrowth (compare dorsal views in L and M with control in K; white bars are of equal length in these panels), so that only the central portion of the eye is in focus in lateral images (E,F,H-J).