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Fig. 4. Histological analysis of mutant OE. (A) Schematic model of mouse OE development. OP, olfactory placode; NP, nasal pit; FB, forebrain; MNP, medial nasal process; LNP, lateral nasal process; S, nasal septum; NC, nasal cavity. (B) Hematoxylin-eosin staining was performed on 20 µm cryosections through the entire frontonasal region of control and mutant embryos from E10.5-E17.5. Scale bar: 200 µm. CP, cartilage primordium of nasal capsule; H, heart; L, lens; MB, midbrain; NR, neural retina; Tel, telencephalon.