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Fig. 4. FGF signaling is necessary and sufficient for induction of Scx in mouse. (A,B) Whole-mount in situ hybridization for Scx on trunks cultured with DMSO (A) or SU5402 (B). (C-F) Whole-mount in situ hybridization for Scx on either wild type (C,D) or Myf5-/-; Myod1-/- (E,F) trunks with either a PBS (C,E) or FGF4 (D,F) bead implanted in somites. (C-F) Asterisks indicate location of beads.