Fig. 4. Localization of pan-Cadherin, E-Cadherin and ß-Catenin in epiblast (ectoderm) and hypoblast (mesendoderm) cells within the shield at the onset of gastrulation (65% epiboly). Frontal sections of the shield region at the margin (A,C,E) and four to six cell diameters away from the margin (B,D,F) stained with an anti-pan-Cadherin (A,B), anti-E-Cadherin (C,D) and anti-ß-Catenin (E,F) antibody. epi, epiblast; hyp, hypoblast. Scale bar in A: 40 µm.