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Fig. 1. Alignments of conserved domains of Gb'hb compared with orthologous sequences from other insects. (A) Four central fingers (MF-1 to 4), two C terminal fingers (CF-1 and 2), and A-Box and C-Box of Gryllus bimaculatus (G.b.) hunchback aligned with those of Schistocerca americana (S.a.), Oncopeltus fasciatus (O.f.), Tribolium castaneum (T.c.) and Drosophila melanogaster (D.m.). Arrowheads indicate the structural residues of the putative metal-binding fingers. (B) Schematic structures of various Hunchback proteins, comparing the organization of zinc fingers. Each box shows a zinc finger or C-box. Corresponding zinc fingers of different species are shown in the same shade. Four central fingers (MF-1 to 4) and two C terminal fingers (CF-1 and 2) are conserved in all insects in this figure. The structure of H.t. Hb was predicted from the genomic sequence (Patel et al., 2001; Savage and Shankland, 1996). C.e., Caenorhabditis elegans; H.t., Helobdella triserialis.