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Figure 7


Fig. 7. Migration of LRN/ECN neurons slowed by cadherin function blocking causes ectopic ipsilateral formation of nuclei. Transverse sections of E18.5 mouse hindbrains electroporated with Venus YFP (A,C,E) and EGFP-NCAD(t) (B,D,F) at E12.5. Lower magnification views (A,B). LRN but not ECN is included in these sections owing to the angle of sectioning. Squares correspond to the higher magnification views in C-F. Asterisks represent the labeled side. Higher magnification views of ipsilateral (C,D) and contralateral (E,F) sides. EGFP-NCAD(t) neurons form a nucleus ipsilaterally unlike control YFP neurons. Scale bars: 600 µm in A,B; 150 µm in C-F.