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Figure 2


Fig. 2. Leftward fluid flow generated by rotational movement of node cilia. (A) Lateral view of a mouse embryo at 8.0 dpc. Scale bar: 100 µm. (B) Monocilia in the node of a mouse embryo shown at high magnification. Scale bar: 1 µm. (C) Ventral view of the node cavity. Anteroposterior (AP) and left-right (LR) orientations are indicated. Red arrow indicates the direction of nodal flow. Scale bar: 10 µm. (D) Ventral view of the node cavity, with fluorescent beads used to visualize fluid flow. The beads move towards the left side of the node (arrow). Scale bar: 10 µm. Image in D courtesy of Shigenori Nonaka (National Institute for Basic Biology, Japan).