Fig. 6. Influence of HES1 activity on retinal proliferation and
differentiation. E5 retinas were co-electroporated with HES1- or
dnHES1-expressing construct and a GFP-expressing construct, and cultured as
explants for 48 hours with BrdU present for the last 3 hours. Effects of HES1
(A,C) or dnHES1 (B,D) on Islet1/2+
(A,B) or BrdU+ (C,D) cells among transfected GFP+ cells
are shown (n=6; *P<0.03).