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Figure 6


Fig. 6. Influence of HES1 activity on retinal proliferation and differentiation. E5 retinas were co-electroporated with HES1- or dnHES1-expressing construct and a GFP-expressing construct, and cultured as explants for 48 hours with BrdU present for the last 3 hours. Effects of HES1 (A,C) or dnHES1 (B,D) on Islet1/2+ (A,B) or BrdU+ (C,D) cells among transfected GFP+ cells are shown (n=6; *P<0.03).