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Figure 1


Fig. 1. Structures of full-length and deleted Ft and Ds proteins. Shown are the cleaved signal sequences (black), cadherin domains (purple), EGF-like domains (green), Laminin-G domains (yellow-green), transmembrane domains (light blue) and the HA tag (dark blue). Sites mutated in ftfd and ftG-rv are also shown. ftfd contains a stop codon in the 9th cadherin domain. ftG-rv contains a mdg3 retrotransposon insertion (the beginning of its sequence is underlined) that introduces a stop codon in the 27th cadherin domain; it also contains additional rearrangements in the first intron and a previously described insertion in the 33rd cadherin domain (not shown) (Mahoney et al., 1991).