Fig. 5. Melanocyte development in Sox10^{Sox8ki/Sox8ki} mice. (A) Comparison of 7-day old Sox10^{Sox8ki/Sox8ki} mice (top) and wild-type littermates (bottom). Sox10^{Sox8ki/Sox8ki} mice are white and smaller than wild type. (B) Skin preparations from 7-day-old wild-type mice and Sox10^{Sox8ki/Sox8ki} littermates shown from the side and from below to visualize hair and hair follicle. (C) Whole-mount in situ hybridization was performed on wild-type and Sox10^{Sox8ki/Sox8ki} embryos at 12.5 dpc using antisense riboprobes against Dct, Kit and Mitf. The regions from which pictures were taken are boxed in the embryo in the lower left corner.