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Figure 9


Fig. 9. Development of oligodendrocyte precursors in Sox10Sox8ki/Sox8ki mice. Specification and subsequent distribution of oligodendrocyte precursors throughout the spinal cord of Sox10Sox8ki/Sox8ki embryos (A-C, G-I, M-O, S-U) and wild-type littermates (D-F, J-L, P-R) was analyzed on transverse sections from the forelimb region at 12.5 dpc (A,D,G,J,M,P,S), 14.5 dpc (B,E,H,K,N,Q,T) and 18.5 dpc (C,F,I,L,O,R,U) using EGFP autofluorescence (A-C) and immunohistochemistry with antibodies directed against Sox8 (D-I), Sox10 (J-O) and Olig2 (P-U).