Fig. 1. Genomic organisation of the dfer locus. (A) In
GAL4MZ465, pGawB (red) is inserted upstream of dfer
(green). The deletions dfer
1
and dfer
ex1 are depicted
(purple). (B) Exon structure of the four predicted dfer
isoforms (a section of the third intron is deleted for clarity). Exon 1 is
non-coding. Additional exons in dferRA and dferRD are in
pink. (C) Predicted protein structure of DFer isoforms. (D)
Molecular map of the dfergof locus. pGawB (red) has
undergone a rearrangement, duplicating and inverting GAL4, and deleting
pBluescript (pBS) and most of mini-white (mw+). (E)
dfergof produces three transcripts, splicing the first
exon of mini white (red) to exons of dfer (green). Light green exons
are spliced out. (F) One transcript (wex1-DFerRB) is predicted
to encode a White-DFer fusion protein.