Fig. 2. Ectopic T expression in ApcMin/Min
epiblast, detected by in situ hybridization with T and Oct4.
(A-C) Ectopic expression of T in the entire epiblast at 5.75 dpc.
Wild-type and mutant VE differ in thickness (arrowheads). (C) Only T
probe was hybridized. (D-G) T and Oct-4 expression in
wild-type and mutant embryos at 4.75 and 3.75 dpc. The arrowhead indicates the
unlabelled PrE. Ep, epiblast; ICM, inner cell mass; Oct4, blue:
T, red.