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Figure 2


Fig. 2. Ectopic T expression in ApcMin/Min epiblast, detected by in situ hybridization with T and Oct4. (A-C) Ectopic expression of T in the entire epiblast at 5.75 dpc. Wild-type and mutant VE differ in thickness (arrowheads). (C) Only T probe was hybridized. (D-G) T and Oct-4 expression in wild-type and mutant embryos at 4.75 and 3.75 dpc. The arrowhead indicates the unlabelled PrE. Ep, epiblast; ICM, inner cell mass; Oct4, blue: T, red.