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Figure 3


Fig. 3. Expression of primitive streak and AVE markers in wild-type and ApcMin/Min embryos. In situ hybridization in 4.75 (A), and 5.5 (B-L) dpc embryos. Double labeling with T and (A) Pem, (B) Gsc or (C) Hex. (D-H) Single labeling of Eomes (D), Otx2 (E), Fgf8 (F), Lhx1 (G), Cer1 (H), Snai1 (I), cripto (J), Nodal (K) and Foxa2 (L). The arrowhead in D indicates a labeled epiblast cell. Ep, epiblast; PE, parietal endoderm; ExE, extraembryonic ectoderm.