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Figure 3


Fig. 3. Wnt-dependent expression of genes associated with primitive streak, EMT, endoderm and mesoderm. ES cells were differentiated in SCM alone or in the presence of Dkk1 (SCM + Dkk1). RNA was isolated at indicated times and analyzed using custom DNA microarrays. Normalized and modeled expression values for the indicated genes in either SCM (solid line) or SCM + Dkk1 (broken line) are expressed in arbitrary units.