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Figure 4


Fig. 4. Meiotic defects in Grip75 and Grip128 mutant eggs. (A-C) DAPI staining of wild-type (A), Grip75175 (B) and Grip128326 mutant (C) stage 14 oocytes. The chromosome arrangement is shown during metaphase arrest. (D-F) Meiosis I spindles in wild-type (D), Grip75175 (E) and Grip128326 mutant (F) eggs. {alpha}-Tubulin is shown in green and DNA in red. (G-J) Meiosis II spindles in wild-type (E), Grip75175 (H) and Grip128326 mutant (J) eggs, stained as in D-F. The arrow indicates the central MTOC in wild type. Confocal stacks were merged into single images.