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Figure 5


Fig. 5. Genetic enhancement of Cv2-/- phenotypes observed by deleting one copy of Bmp4. (A-F) Skeletal samples of P0 neonates. Lumbar vertebrae. (A-C) Frontal view. (D-F) Left lateral view. Arrow, ossification of the vertebral body; arrowhead, ossifying part of the vertebral arch. (G-I) External appearance of P0 neonate heads. Arrowhead, missing eye. Cv2+/-;Bmp4+/- (A,D,G), Cv2-/-;Bmp4+/+ (B,E,H) and Cv2-/-;Bmp4+/- (C,F,I) mice.