Fig. 3. Developmental abnormality of Bhlhb5-null retinas. (A-J) Retinal sections from Bhlhb5^-/- and wild-type control retinas at indicated developmental stages were stained with Haemotoxylin and Eosin. Compared with the control retina (A,C,E), no overt change in retinal thickness and laminar organization is seen in the mutant (B,D,F) from E15.5-P0. At P14 to P28, the INL of Bhlhb5-null retinas is thinner and the number of cells in the INL is reduced by approximately 40% (G-J). (K) Quantitation of cells in the INL and the GCL per 250 µm length of retinal section at E17.5 to P28. Each bar represents the mean±s.d. for three or more retinas. Scale bars: 50 µm.