Fig. 3. DNA binding and transcriptional repression by Nkx3.2 are required to block chondrocyte maturation. The right forelimb buds of day 3 chick embryos were infected with RCAS viruses encoding mutant forms of Nkx3.2, as indicated. The embryos were harvested at E10 for skeletal preparation (A-F), or section ISH (G-L) with the indicated probes.