Fig. 1. Expression of Fez during mouse development. (A-K) Expression of Fez at E8.0 (A), E8.5 (B), E9.5 (C), E10.5 (D), E12.5 (E-I) and E15.5 (J,K). (A-D) Whole-mount in situ hybridization, lateral views with anterior to the left. (E-K) In situ hybridization of coronal sections from the anterior (E) to the posterior (H), and coronal sections of the olfactory epithelium (I-K) and the olfactory bulb (K). Fez transcripts were detected in the olfactory epithelium (black arrowheads; E,I,J,K), septum (black arrow, E), roof of the telencephalon (F), hypothalamus (asterisks; G,H), prethalamus (black arrowhead, G) and amygdala (black arrows; G,H), but not in the olfactory bulb (black arrows in K). (I) High-magnification view of the olfactory epithelium. Fez expression was detected in the olfactory epithelium, but was scarce in the vomeronasal organs (VNO, white arrowheads in E,I).