(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 5


Fig. 5. Ncx4a is required for heart and gut LR patterning in zebrafish. (A-F) Expression pattern of the genes encoding Na,K-ATPase {alpha}2 and Ncx4a. Transcripts encoding Na,K-ATPase {alpha}2 (A) and Ncx4a (D) are detected prior to the mid-blastula stage. By the 10-somite stage, Na,K-ATPase {alpha}2 (B) and Ncx4a (E) are expressed in a broad range of tissues including Kupffer's vesicle (kv, arrow). By the 24-somite stage, Na,K-ATPase {alpha}2 is expressed predominantly in the somites (C), whereas Ncx4a remains ubiquitous (F). (G) Bar chart of the percentage of embryos exhibiting heart and/or gut laterality defects.