Fig. 3. Expression pattern of Gata3 during the cell cycle. Gata3 expression is visualized by in situ hybridization in the control (A,B,F,J), or by X-Gal staining in the Gata3 LacZ knockin skin (C-E,G-I,K,L). At E15.5 there is strong expression of Gata3 in the epidermis (A). During anagen (A, P3), Gata3 is highly expressed in the IRS, ORS, sebaceous glands (black arrowhead), epidermis and infundibulum (arrows) (B-F,I-L,), and closer inspection (L) reveals that some cells in the germinative layer around the dermal papilla are also Gata3 positive (white arrowhead). During catagen, Gata3 expression was restricted to the IRS (G) and was absent in HF during telogen but present in the epidermis and sebaceous gland (H). Scale bar in A: 200 µm for D,K; 150 µm for A-C,F,G-J,L; 50 µm for E.