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Figure 5


Fig. 5. Rescued insulin-positive cells are present by E13.5 and do not abnormally co-express the hormone ghrelin. (A,B) Insulin-positive (red, arrows) cells are found at E13.5 in Nkx2.2-/-;Nkx2.2hdEnR embryos (n=4 embryos each). (C,D) Insulin (red) is not co-expressed with ghrelin (green) at E18.5 in either wild-type (C) or Nkx2.2-/-;2.2hdEnR (D) embryos. (20x magnification.)