(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Model of Nrp1a-Sema3D-mediated guidance of left habenular axons. (A) Sema3D attracts Nrp1a-expressing growth cones of left habenular axons toward the dorsal IPN. Following Nrp1a (B) or Sema3D (C) depletion, left habenular efferents innervate only the ventral IPN, similar to right habenular neurons that do not express nrp1a. (D) Sema3D overexpression can result in ectopic habenular projections that extend beyond the dorsal IPN.