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Figure 5


Fig. 5. Epithelial polarity in par-6(M/Z) embryos. (A-B') Microtubules in wild-type (A,A') and par-6(M/Z) (B,B') embryos concentrate at apical regions of intestinal epithelial cells (arrows in A',B'); embryos are co-stained for {alpha}-tubulin and PAR-6. (C-E) IFB-2 localization in intestinal cells of wild-type and par-6(M/Z) embryos. IFB-2 localizes in a continuous apical band in wild type (C). In younger par-6(M/Z) embryos (D), IFB-2 is apical but not always continuous between cells (arrow); (E) apical IFB-2 patches separate and circularize (arrow) in older par-6(M/Z) embryos. Scale bars: 2.5 µm.