Fig. 6. p75^NTR expression in sympathetic neurons is dependent on CREB. Non-radioactive in situ hybridization with a riboprobe specific for the p75^NTR on representative sagittal sections from control (A,C) and Creb^DBHCre; Crem^-/- (B,D) showing the SCG (A,B) and basal cholinergic neurons (C,D) at E17.5. Asterisk indicates the inner ear. Immunohistochemistry with an antibody recognizing the p75^NTR protein is used to analyze protein expression in the SCG at E17.5 in controls (E) and in Creb^DBHCre; Crem^-/- (F). Scale bar: 250 µm in A-D; 40 µm in E,F; 20 µm in insets.