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Figure 1


Fig. 1. PDGFR{alpha}, PDGFRβ and Pax3 mRNA expression at st. 8 and 10. (A) PDGFR{alpha} is expressed in the head and somites at st. 8 in whole mount. (B) In section, PDGFR{alpha} is detected in the midbrain-level mesenchyme. (C) At st. 10, PDGFR{alpha} is in neural crest and somites. (D) Migrating neural crest cells express PDGFR{alpha} at the midbrain-level at st. 10. (E,F) PDGFRβ is strongly expressed in ectoderm and neural folds at st. 8. (G,H) PDGFRβ is maintained in ectoderm at st.10. (I,J) Pax3 is absent from presumptive opV trigeminal placode at st. 8. (K,L) Pax3 marks opV trigeminal placode ectoderm and early migrating neural crest at midbrain level. Broken white lines in whole mounts (A,C,E,G,I,K) indicate level of section (B,D,F,H,J,L). ECTO, ectoderm; MES, mesenchyme; NF, neural folds; NC, neural crest.