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Figure 3


Fig. 3. Oligodendrocyte development in Sox9loxP/loxP, Sox10::Cre spinal cords. Immunohistochemistry with antibodies specific for Sox10 (A-D), Olig2 (E-H), Pdgfra (I-L) and in situ hybridizations with a Plp-specific probe (M,N) were performed on transverse sections from the forelimb region of wild-type (A,C,E,G,I,K,M) or Sox9loxP/loxP, Sox10::Cre (Sox9{Delta}/{Delta}) (B,D,F,H,J,L,N) embryos at 15.5 dpc (A,B,E,F,I,J) and 18.5 dpc (C,D,G,H,K,L,M,N).