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Development, Vol 103, Issue 1 157-170, Copyright © 1988 by Company of Biologists
JOURNAL ARTICLES |
A Martizez Arias, NE Baker and PW Ingham
MRC Laboratory of Molecular Biology, Cambridge, UK.
Segment polarity genes are expressed and required in restricted domains within each metameric unit of the Drosophila embryo. We have used the expression of two segment polarity genes engrailed (en) and wingless (wg) to monitor the effects of segment polarity mutants on the basic metameric pattern. Absence of patched (ptc) or naked (nkd) functions triggers a novel sequence of en and wg patterns. In addition, although wg and en are not expressed on the same cells absence of either one has effects on the expression of the other. These observations, together with an analysis of mutant phenotypes during development, lead us to suggest that positional information is encoded in cell states defined and maintained by the activity of segment polarity gene products.
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A. Manoukian, K. Yoffe, E. Wilder, and N Perrimon The porcupine gene is required for wingless autoregulation in Drosophila Development, January 12, 1995; 121(12): 4037 - 4044. [Abstract] [PDF]
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C Ma and K Moses Wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye Development, January 8, 1995; 121(8): 2279 - 2289. [Abstract] [PDF]
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C Schwartz, J Locke, C Nishida, and T. Kornberg Analysis of cubitus interruptus regulation in Drosophila embryos and imaginal disks Development, January 6, 1995; 121(6): 1625 - 1635. [Abstract] [PDF]
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A John, S. Smith, and J. Jaynes Inserting the Ftz homeodomain into engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo Development, January 6, 1995; 121(6): 1801 - 1813. [Abstract] [PDF]
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L Maves and G Schubiger Wingless induces transdetermination in developing Drosophila imaginal discs Development, January 5, 1995; 121(5): 1263 - 1272. [Abstract] [PDF]
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A. Felsenfeld and J. Kennison Positional signaling by hedgehog in Drosophila imaginal disc development Development, January 1, 1995; 121(1): 1 - 10. [Abstract] [PDF]
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M Peifer The two faces of hedgehog Science, December 2, 1994; 266(5190): 1492 - 1493. [PDF]
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J. Lee, S. Ekker, D. von Kessler, J. Porter, B. Sun, and P. Beachy Autoproteolysis in hedgehog protein biogenesis Science, December 2, 1994; 266(5190): 1528 - 1537. [Abstract] [PDF]
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K M Cadigan, U Grossniklaus, and W J Gehring Localized expression of sloppy paired protein maintains the polarity of Drosophila parasegments. Genes & Dev., April 15, 1994; 8(8): 899 - 913. [Abstract] [PDF]
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P. Lawrence, P Johnston, and J. Vincent Wingless can bring about a mesoderm-to-ectoderm induction in Drosophila embryos Development, January 12, 1994; 120(12): 3355 - 3359. [Abstract] [PDF]
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D. Chang, A Lopez, D. von Kessler, C Chiang, B. Simandl, R Zhao, M. Seldin, J. Fallon, and P. Beachy Products, genetic linkage and limb patterning activity of a murine hedgehog gene Development, January 11, 1994; 120(11): 3339 - 3353. [Abstract] [PDF]
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W Wurst, A. Auerbach, and A. Joyner Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum Development, January 7, 1994; 120(7): 2065 - 2075. [Abstract] [PDF]
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F. Diaz-Benjumea and S. Cohen wingless acts through the shaggy/zeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg Development, January 6, 1994; 120(6): 1661 - 1670. [Abstract] [PDF]
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P. Salinas, C Fletcher, N. Copeland, N. Jenkins, and R Nusse Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells Development, January 5, 1994; 120(5): 1277 - 1286. [Abstract] [PDF]
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J Capdevila, F Pariente, J Sampedro, J. Alonso, and I Guerrero Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos Development, January 4, 1994; 120(4): 987 - 998. [Abstract] [PDF]
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T Volk and K VijayRaghavan A central role for epidermal segment border cells in the induction of muscle patterning in the Drosophila embryo Development, January 1, 1994; 120(1): 59 - 70. [Abstract] [PDF]
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M J Benedyk, J R Mullen, and S DiNardo odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos. Genes & Dev., January 1, 1994; 8(1): 105 - 117. [Abstract] [PDF]
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J Klingensmith, R Nusse, and N Perrimon The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes & Dev., January 1, 1994; 8(1): 118 - 130. [Abstract] [PDF]
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P. A. Lawrence and J. Sampedro Drosophila segmentation: after the first three hours Development, December 1, 1993; 119(4): 971 - 976. [PDF]
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C. R. Hume and J. |
