|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 121, Issue 1 189-200, Copyright © 1995 by Company of Biologists
JOURNAL ARTICLES |
M Yamagata and JR Sanes
Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO 63110.
In the chick, retinal axons enter the optic tectum through a superficial lamina, then branch into distinct deeper retinorecipient laminae, where they arborize and form synapses. To study factors that guide this laminar selectivity, we devised an organotypic culture system in which a transverse tectal section is overlaid with a retinal explant large enough to allow unimpeded access to all tectal laminae. Outgrowth, branching, and arborization patterns of retinal axons on tectal slices were lamina-selective, indicating the existence of localized cues that guide retinal axons. Further studies suggested that some of these cues are: (1) associated with cell membranes or extracellular matrix (because axons grew selectively on chemically fixed tectal sections); (2) intrinsic to the tectum (because axons grew selectively on tectal sections prepared from enucleated embryos); (3) distinct from topographic cues (because axons from nasal and temporal retina behaved similarly on anterior tectal slices); and (4) selective for retinal axons (because axons growing from other explants exhibited different laminar preferences).
This article has been cited by other articles:
|
|
 |
|
  N. Tian Synaptic activity, visual experience and the maturation of retinal synaptic circuitry J. Physiol., September 15, 2008; 586(18): 4347 - 4355. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Godinho, J. S. Mumm, P. R. Williams, E. H. Schroeter, A. Koerber, S. W. Park, S. D. Leach, and R. O. L. Wong Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina Development, November 15, 2005; 132(22): 5069 - 5079. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Yamagata and J. R. Sanes Versican in the Developing Brain: Lamina-Specific Expression in Interneuronal Subsets and Role in Presynaptic Maturation J. Neurosci., September 14, 2005; 25(37): 8457 - 8467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Uesaka, S. Hirai, T. Maruyama, E. S. Ruthazer, and N. Yamamoto Activity Dependence of Cortical Axon Branch Formation: A Morphological and Electrophysiological Study Using Organotypic Slice Cultures J. Neurosci., January 5, 2005; 25(1): 1 - 9. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Sugiyama and H. Nakamura The role of Grg4 in tectal laminar formation Development, February 1, 2003; 130(3): 451 - 462. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Treubert-Zimmermann, D. Heyers, and C. Redies Targeting Axons to Specific Fiber Tracts In Vivo by Altering Cadherin Expression J. Neurosci., September 1, 2002; 22(17): 7617 - 7626. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Sakurai, E. Wong, U. Drescher, H. Tanaka, and D. G. Jay Ephrin-A5 restricts topographically specific arborization in the chick retinotectal projection in vivo PNAS, August 6, 2002; 99(16): 10795 - 10800. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Yamamoto, K. Inui, Y. Matsuyama, A. Harada, K. Hanamura, F. Murakami, E. S. Ruthazer, U. Rutishauser, and T. Seki Inhibitory Mechanism by Polysialic Acid for Lamina-Specific Branch Formation of Thalamocortical Axons J. Neurosci., December 15, 2000; 20(24): 9145 - 9151. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Yagi and M. Takeichi Cadherin superfamily genes: functions, genomic organization, and neurologic diversity Genes & Dev., May 15, 2000; 14(10): 1169 - 1180. [Full Text]
|
|
|
|
|
|
W. T. Wong, J. R. Sanes, and R. O. L. Wong Developmentally Regulated Spontaneous Activity in the Embryonic Chick Retina J. Neurosci., November 1, 1998; 18(21): 8839 - 8852. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Zhang and D. S. Galileo Retroviral Transfer of Antisense Integrin alpha 6 or alpha 8 Sequences Results in Laminar Redistribution or Clonal Cell Death in Developing Brain J. Neurosci., September 1, 1998; 18(17): 6928 - 6938. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Albertinazzi, D. Gilardelli, S. Paris, R. Longhi, and I. de Curtis Overexpression of a Neural-specific Rho Family GTPase, cRac1B, Selectively Induces Enhanced Neuritogenesis and Neurite Branching in Primary Neurons J. Cell Biol., August 10, 1998; 142(3): 815 - 825. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Yamamoto, S. Higashi, and K. Toyama Stop and Branch Behaviors of Geniculocortical Axons: A Time-Lapse Study in Organotypic Cocultures J. Neurosci., May 15, 1997; 17(10): 3653 - 3663. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N Soussi-Yanicostas, J. Hardelin, M. Arroyo-Jimenez, O Ardouin, R Legouis, J Levilliers, F Traincard, J. Betton, L Cabanie, and C Petit Initial characterization of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous system J. Cell Sci., January 7, 1996; 109(7): 1749 - 1757. [Abstract] [PDF]
|
|
|
|
|
|
M Yamagata and J. Sanes Target-independent diversification and target-specific projection of chemically defined retinal ganglion cell subsets Development, January 11, 1995; 121(11): 3763 - 3776. [Abstract] [PDF]
|
|
