|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 125, Issue 6 1083-1093, Copyright © 1998 by Company of Biologists
JOURNAL ARTICLES |
RD Burdine, CS Branda and MJ Stern
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520-8005, USA.
During the development of the egg-laying system in Caenorhabditis elegans hermaphrodites, central gonadal cells organize the alignment of the vulva with the sex myoblasts, the progenitors of the egg-laying muscles. A fibroblast growth factor [EGL-17(FGF)] and an FGF receptor [EGL-15(FGFR)] are involved in the gonadal signals that guide the migrations of the sex myoblasts. Here we show that EGL-17(FGF) can act as an instructive guidance cue to direct the sex myoblasts to their final destinations. We find that egl-17 reporter constructs are expressed in the primary vulval cell and that EGL-17(FGF) expression in this cell correlates with the precise positioning of the sex myoblasts. We postulate that EGL-17(FGF) helps to coordinate the development of a functional egg-laying system, linking vulval induction with proper sex myoblast migration.
This article has been cited by other articles:
|
|
 |
|
  T. O. Ririe, J. S. Fernandes, and P. W. Sternberg Gene Networks in Development and Evolution Special Feature Sackler Colloquium: The Caenorhabditis elegans vulva: A post-embryonic gene regulatory network controlling organogenesis PNAS, December 23, 2008; 105(51): 20095 - 20099. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. R. Myers and I. Greenwald Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans PNAS, December 18, 2007; 104(51): 20368 - 20373. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Kuroyanagi, G. Ohno, S. Mitani, and M. Hagiwara The Fox-1 Family and SUP-12 Coordinately Regulate Tissue-Specific Alternative Splicing In Vivo Mol. Cell. Biol., December 15, 2007; 27(24): 8612 - 8621. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. de Souza, L. G. Vallier, H. Fares, and I. Greenwald SEL-2, the C. elegans neurobeachin/LRBA homolog, is a negative regulator of lin-12/Notch activity and affects endosomal traffic in polarized epithelial cells Development, February 15, 2007; 134(4): 691 - 702. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Nechiporuk, T. Linbo, K. D. Poss, and D. W. Raible Specification of epibranchial placodes in zebrafish Development, February 1, 2007; 134(3): 611 - 623. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Podbilewicz and Y. Gruenbaum Live Imaging of Caenorhabditis elegans: Examples CSH Protocols, November 1, 2006; 2006(29): pdb.ip19 - pdb.ip19. [Full Text]
|
|
|
|
|
|
C. B. Walser, G. Battu, E. F. Hoier, and A. Hajnal Distinct roles of the Pumilio and FBF translational repressors during C. elegans vulval development Development, September 1, 2006; 133(17): 3461 - 3471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Dixon, M. Alexander, R. Fernandes, N. Ricker, and P. J. Roy FGF negatively regulates muscle membrane extension in Caenorhabditis elegans Development, April 1, 2006; 133(7): 1263 - 1275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. S. Yoo and I. Greenwald LIN-12/Notch Activation Leads to MicroRNA-Mediated Down-Regulation of Vav in C. elegans Science, November 25, 2005; 310(5752): 1330 - 1333. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. D. Shaye and I. Greenwald LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans Development, November 15, 2005; 132(22): 5081 - 5092. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. C. Fleming, F. W. Wolf, and G. Garriga Sensitized genetic backgrounds reveal a role for C. elegans FGF EGL-17 as a repellent for migrating CAN neurons Development, November 1, 2005; 132(21): 4857 - 4867. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Jiang, V. Horner, and J. Liu The HMX homeodomain protein MLS-2 regulates cleavage orientation, cell proliferation and cell fate specification in the C. elegans postembryonic mesoderm Development, September 15, 2005; 132(18): 4119 - 4130. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. A. Berset, E. F. Hoier, and A. Hajnal The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions Genes & Dev., June 1, 2005; 19(11): 1328 - 1340. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Inoue, M. Wang, T. O. Ririe, J. S. Fernandes, and P. W. Sternberg Gene Regulatory Networks Special Feature: Transcriptional network underlying Caenorhabditis elegans vulval development PNAS, April 5, 2005; 102(14): 4972 - 4977. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Dalpe, L. Brown, and J. G. Culotti Vulva morphogenesis involves attraction of plexin 1-expressing primordial vulva cells to semaphorin 1a sequentially expressed at the vulva midline Development, March 15, 2005; 132(6): 1387 - 1400. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. E. Sasson and M. J. Stern FGF and PI3 kinase signaling pathways antagonistically modulate sex muscle differentiation in C. elegans Development, November 1, 2004; 131(21): 5381 - 5392. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Huang and M. J. Stern FGF signaling functions in the hypodermis to regulate fluid balance in C. elegans Development, June 1, 2004; 131(11): 2595 - 2604. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Stathopoulos, B. Tam, M. Ronshaugen, M. Frasch, and M. Levine pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos Genes & Dev., March 15, 2004; 18(6): 687 - 699. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Yoo, C. Bais, and I. Greenwald Crosstalk Between the EGFR and LIN-12/Notch Pathways in C. elegans Vulval Development Science, January 30, 2004; 303(5658): 663 - 666. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Kamikura and J. A. Cooper Lipoprotein receptors and a Disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans Genes & Dev., November 15, 2003; 17(22): 2798 - 2811. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Goodman, C. S. Branda, M. K. Robinson, R. D. Burdine, and M. J. Stern Alternative splicing affecting a novel domain in the C. elegans EGL-15 FGF receptor confers functional specificity Development, August 15, 2003; 130(16): 3757 - 3766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Huang, P. Huang, M. K. Robinson, M. J. Stern, and Y. Jin UNC-71, a disintegrin and metalloprotease (ADAM) protein, regulates motor axon guidance and sex myoblast migration in C. elegans Development, July 15, 2003; 130(14): 3147 - 3161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. P. Gupta, M. Wang, and P. W. Sternberg The C. elegans LIM homeobox gene lin-11 specifies multiple cell fates during vulval development Development, June 15, 2003; 130(12): 2589 - 2601. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Howard and M. V. Sundaram C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component Genes & Dev., July 15, 2002; 16(14): 1815 - 1827. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Dufourcq, M. Victor, F. Gay, D. Calvo, J. Hodgkin, and Y. Shi Functional Requirement for Histone Deacetylase 1 in Caenorhabditis elegans Gonadogenesis Mol. Cell. Biol., May 1, 2002; 22(9): 3024 - 3034. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Jungblut, A. Pires-daSilva, and R. J. Sommer Formation of the egg-laying system in Pristionchus pacificus requires complex interactions between gonadal, mesodermal and epidermal tissues and does not rely on single cell inductions Development, September 15, 2001; 128(18): 3395 - 3404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T von Zelewsky, F Palladino, K Brunschwig, H Tobler, A Hajnal, and F Muller The C. elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination Development, January 12, 2000; 127(24): 5277 - 5284. [Abstract] [PDF]
|
|
|
|
|
|
D. Fay and M Han Mutations in cye-1, a Caenorhabditis elegans cyclin E homolog, reveal coordination between cell-cycle control and vulval development Development, January 9, 2000; 127(18): 4049 - 4060. [Abstract] [PDF]
|
|
|
|
|
|
N Pujol, P Torregrossa, J. Ewbank, and J. Brunet The homeodomain protein CePHOX2/CEH-17 controls antero-posterior axonal growth in C. elegans Development, January 8, 2000; 127(15): 3361 - 3371. [Abstract] [PDF]
|
|
|
|
|
|
M Weaver, N. Dunn, and B. Hogan Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis Development, January 6, 2000; 127(12): 2695 - 2704. [Abstract] [PDF]
|
|
|
|
|
|
P. Clow, T Chen, R. Chisholm, and J. McNally Three-dimensional in vivo analysis of Dictyostelium mounds reveals directional sorting of prestalk cells and defines a role for the myosin II regulatory light chain in prestalk cell sorting and tip protrusion Development, January 6, 2000; 127(12): 2715 - 2728. [Abstract] [PDF]
|
|
|
|
|
|
L. I. Jiang and P. W. Sternberg An HMG1-like protein facilitates Wnt signaling in Caenorhabditis elegans Genes & Dev., April 1, 1999; 13(7): 877 - 889. [Abstract] [Full Text]
|
|
|
|
|
|
V Ambros Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells Development, January 5, 1999; 126(9): 1947 - 1956. [Abstract] [PDF]
|
|
|
|
|
|
G. R. Martin The roles of FGFs in the early development of vertebrate limbs Genes & Dev., June 1, 1998; 12(11): 1571 - 1586. [Full Text]
|
|
|
|
|
|
Y Hong, R Roy, and V Ambros Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans Development, January 9, 1998; 125(18): 3585 - 3597. [Abstract] [PDF]
|
|
|
|
|
|
D Levitan and I Greenwald LIN-12 protein expression and localization during vulval development in C. elegans Development, January 8, 1998; 125(16): 3101 - 3109. [Abstract] [PDF]
|
|
|
|
|
|
T. Berset, E. F. Hoier, G. Battu, S. Canevascini, and A. Hajnal Notch Inhibition of RAS Signaling Through MAP Kinase Phosphatase LIP-1 During C. elegans Vulval Development Science, February 9, 2001; 291(5506): 1055 - 1058. [Abstract] [Full Text]
|
|
