spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Daubresse, G.
Right arrow Articles by Tamkun, J. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Daubresse, G.
Right arrow Articles by Tamkun, J. W.

Development, Vol 126, Issue 6 1175-1187, Copyright © 1999 by Company of Biologists

JOURNAL ARTICLES

The Drosophila kismet gene is related to chromatin-remodeling factors and is required for both segmentation and segment identity

G Daubresse, R Deuring, L Moore, O Papoulas, I Zakrajsek, WR Waldrip, MP Scott, JA Kennison and JW Tamkun
Department of Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.

The Drosophila kismet gene was identified in a screen for dominant suppressors of Polycomb, a repressor of homeotic genes. Here we show that kismet mutations suppress the Polycomb mutant phenotype by blocking the ectopic transcription of homeotic genes. Loss of zygotic kismet function causes homeotic transformations similar to those associated with loss-of-function mutations in the homeotic genes Sex combs reduced and Abdominal-B. kismet is also required for proper larval body segmentation. Loss of maternal kismet function causes segmentation defects similar to those caused by mutations in the pair-rule gene even-skipped. The kismet gene encodes several large nuclear proteins that are ubiquitously expressed along the anterior-posterior axis. The Kismet proteins contain a domain conserved in the trithorax group protein Brahma and related chromatin-remodeling factors, providing further evidence that alterations in chromatin structure are required to maintain the spatially restricted patterns of homeotic gene transcription.


This article has been cited by other articles:


Home page
 DevelopmentHome page
S. Petruk, S. T. Smith, Y. Sedkov, and A. Mazo
Association of trxG and PcG proteins with the bxd maintenance element depends on transcriptional activity
Development, July 15, 2008; 135(14): 2383 - 2390.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
B. A. Thompson, V. Tremblay, G. Lin, and D. A. Bochar
CHD8 Is an ATP-Dependent Chromatin Remodeling Factor That Regulates {beta}-Catenin Target Genes
Mol. Cell. Biol., June 15, 2008; 28(12): 3894 - 3904.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
K. W. Trotter, H.-Y. Fan, M. L. Ivey, R. E. Kingston, and T. K. Archer
The HSA Domain of BRG1 Mediates Critical Interactions Required for Glucocorticoid Receptor-Dependent Transcriptional Activation In Vivo
Mol. Cell. Biol., February 15, 2008; 28(4): 1413 - 1426.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
I. E. McDaniel, J. M. Lee, M. S. Berger, C. K. Hanagami, and J. A. Armstrong
Investigations of CHD1 Function in Transcription and Development of Drosophila melanogaster
Genetics, January 1, 2008; 178(1): 583 - 587.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
B. Papp and J. Muller
Histone trimethylation and the maintenance of transcriptional ONand OFF states by trxG and PcG proteins
Genes & Dev., August 1, 2006; 20(15): 2041 - 2054.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. Flaus, D. M. A. Martin, G. J. Barton, and T. Owen-Hughes
Identification of multiple distinct Snf2 subfamilies with conserved structural motifs
Nucleic Acids Res., May 31, 2006; 34(10): 2887 - 2905.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
R. Xi and T. Xie
Stem Cell Self-Renewal Controlled by Chromatin Remodeling Factors
Science, December 2, 2005; 310(5753): 1487 - 1489.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. Singh, J. Chan, J. J. Chern, and K.-W. Choi
Genetic Interaction of Lobe With Its Modifiers in Dorsoventral Patterning and Growth of the Drosophila Eye
Genetics, September 1, 2005; 171(1): 169 - 183.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
S. Srinivasan, J. A. Armstrong, R. Deuring, I. K. Dahlsveen, H. McNeill, and J. W. Tamkun
The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II
Development, April 1, 2005; 132(7): 1623 - 1635.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. Luschnig, B. Moussian, J. Krauss, I. Desjeux, J. Perkovic, and C. Nusslein-Volhard
An F1 Genetic Screen for Maternal-Effect Mutations Affecting Embryonic Pattern Formation in Drosophila melanogaster
Genetics, May 1, 2004; 167(1): 325 - 342.
[Abstract] [Full Text] [PDF]

Home page
 Microbiol. Mol. Biol. Rev.Home page
K. A. Borkovich, L. A. Alex, O. Yarden, M. Freitag, G. E. Turner, N. D. Read, S. Seiler, D. Bell-Pedersen, J. Paietta, N. Plesofsky, et al.
Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism
Microbiol. Mol. Biol. Rev., March 1, 2004; 68(1): 1 - 108.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
D. V. Fyodorov, M. D. Blower, G. H. Karpen, and J. T. Kadonaga
Acf1 confers unique activities to ACF/CHRAC and promotes the formation rather than disruption of chromatin in vivo
Genes & Dev., January 15, 2004; 18(2): 170 - 183.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
F. Janody, J. D. Lee, N. Jahren, D. J. Hazelett, A. Benlali, G. I. Miura, I. Draskovic, and J. E. Treisman
A Mosaic Genetic Screen Reveals Distinct Roles for trithorax and Polycomb Group Genes in Drosophila Eye Development
Genetics, January 1, 2004; 166(1): 187 - 200.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
P. J. Clyne, J. S. Brotman, S. T. Sweeney, and G. Davis
Green Fluorescent Protein Tagging Drosophila Proteins at Their Native Genomic Loci With Small P Elements
Genetics, November 1, 2003; 165(3): 1433 - 1441.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Salvaing, A. Lopez, A. Boivin, J. S. Deutsch, and F. Peronnet
The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor
Nucleic Acids Res., June 1, 2003; 31(11): 2873 - 2882.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
K. Tajul-Arifin, R. Teasdale, T. Ravasi, D. A. Hume, RIKEN GER Group, GSL Members, and J. S. Mattick
Identification and Analysis of Chromodomain-Containing Proteins Encoded in the Mouse Transcriptome
Genome Res., June 1, 2003; 13(6): 1416 - 1429.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
L. Gutierrez, M. Zurita, J. A. Kennison, and M. Vazquez
The Drosophila trithorax group gene tonalli(tna) interacts genetically with the Brahma remodeling complex and encodes an SP-RING finger protein
Development, March 2, 2003; 130(2): 343 - 354.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
I. F. G. King, N. J. Francis, and R. E. Kingston
Native and Recombinant Polycomb Group Complexes Establish a Selective Block to Template Accessibility To Repress Transcription In Vitro
Mol. Cell. Biol., November 15, 2002; 22(22): 7919 - 7928.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. T. Pena-Rangel, I. Rodriguez, and J. R. Riesgo-Escovar
A Misexpression Study Examining Dorsal Thorax Formation in Drosophila melanogaster
Genetics, March 1, 2002; 160(3): 1035 - 1050.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. Calgaro, M. Boube, D. L. Cribbs, and H.-M. Bourbon
The Drosophila Gene taranis Encodes a Novel Trithorax Group Member Potentially Linked to the Cell Cycle Regulatory Apparatus
Genetics, February 1, 2002; 160(2): 547 - 560.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
T. Doerks, R. R. Copley, J. Schultz, C. P. Ponting, and P. Bork
Systematic Identification of Novel Protein Domain Families Associated with Nuclear Functions
Genome Res., January 1, 2002; 12(1): 47 - 56.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Ruhf, A Braun, O Papoulas, J. Tamkun, N Randsholt, and M Meister
The domino gene of Drosophila encodes novel members of the SWI2/SNF2 family of DNA-dependent ATPases, which contribute to the silencing of homeotic genes
Development, January 4, 2001; 128(8): 1429 - 1441.
[Abstract] [PDF]

Home page
 GeneticsHome page
M. Decoville, E. Giacomello, M. Leng, and D. Locker
DSP1, an HMG-like Protein, Is Involved in the Regulation of Homeotic Genes
Genetics, January 1, 2001; 157(1): 237 - 244.
[Abstract] [Full Text]

Home page
 GeneticsHome page
M. Therrien, D. K. Morrison, A. M. Wong, and G. M. Rubin
A Genetic Screen for Modifiers of a Kinase Suppressor of Ras-Dependent Rough Eye Phenotype in Drosophila
Genetics, November 1, 2000; 156(3): 1231 - 1242.
[Abstract] [Full Text]

Home page
 Nucleic Acids ResHome page
A. Carr and M. D. Biggin
Accessibility of transcriptionally inactive genes is specifically reduced at homeoprotein-DNA binding sites in Drosophila
Nucleic Acids Res., July 15, 2000; 28(14): 2839 - 2846.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
E. Wiellette, K. Harding, K. Mace, M. Ronshaugen, F. Wang, and W McGinnis
spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk
Development, January 12, 1999; 126(23): 5373 - 5385.
[Abstract] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
O. Papoulas, G. Daubresse, J. A. Armstrong, J. Jin, M. P. Scott, and J. W. Tamkun
The HMG-domain protein BAP111 is important for the function of the BRM chromatin-remodeling complex invivo
PNAS, May 8, 2001; 98(10): 5728 - 5733.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 1999