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Development, Vol 127, Issue 22 4743-4752, Copyright © 2000 by Company of Biologists


JOURNAL ARTICLES

HyAlx, an aristaless-related gene, is involved in tentacle formation in hydra

KM Smith, L Gee and HR Bode
Developmental Biology Center, and Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA. hrbode@uci.edu

Developmental gradients are known to play important roles in axial patterning in hydra. Current efforts are directed toward elucidating the molecular basis of these gradients. We report the isolation and characterization of HyAlx, an aristaless-related gene in hydra. The expression patterns of the gene in adult hydra, as well as during bud formation, head regeneration and the formation of ectopic head structures along the body column, indicate the gene plays a role in the specification of tissue for tentacle formation. The use of RNAi provides more direct evidence for this conclusion. The different patterns of HyAlx expression during head regeneration and bud formation also provide support for a recent version of a reaction-diffusion model for axial patterning in hydra.


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