QUICK SEARCH:   [advanced] Author: Keyword(s):
Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents

First published online March 15, 2004
doi: 10.1242/10.1242/dev.01089

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Shah, M. M. Articles by Nigam, S. K. Search for Related Content PubMed PubMed Citation Articles by Shah, M. M. Articles by Nigam, S. K.

Branching morphogenesis and kidney disease

Mita M. Shah^*, Rosemary V. Sampogna^*, Hiroyuki Sakurai, Kevin T. Bush and Sanjay K. Nigam

Departments of Pediatrics, Medicine, and Cellular and Molecular Medicine, University of California, San Diego, CA 92093-0693, USA

Author for correspondence (e-mail: snigam{at}ucsd.edu)

SUMMARY

Branching morphogenesis in the kidney is a tightly regulated, complex process and its disruption potentially can lead to a broad spectrum of diseases, ranging from rare hereditary syndromes to common conditions such as hypertension and chronic kidney failure. This review synthesizes data on branching during kidney development derived from in vitro and in vivo rodent studies and to apply them to human diseases. It discusses how the broad organization of molecular interactions during kidney development might provide a mechanistic framework for understanding disorders related to aberrant branching.

This article has been cited by other articles:

				F. Desmots, H. R. Russell, Y. Lee, K. Boyd, and P. J. McKinnon The Reaper-Binding Protein Scythe Modulates Apoptosis and Proliferation during Mammalian Development Mol. Cell. Biol., December 1, 2005; 25(23): 10329 - 10337. [Abstract] [Full Text] [PDF]

				H. Dickinson, D. W. Walker, L. Cullen-McEwen, E. M. Wintour, and K. Moritz The spiny mouse (Acomys cahirinus) completes nephrogenesis before birth Am J Physiol Renal Physiol, August 1, 2005; 289(2): F273 - F279. [Abstract] [Full Text] [PDF]

				T. Morinaga, A. Enomoto, Y. Shimono, F. Hirose, N. Fukuda, A. Dambara, M. Jijiwa, K. Kawai, K. Hashimoto, M. Ichihara, et al. GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region Nucleic Acids Res., July 26, 2005; 33(13): 4191 - 4201. [Abstract] [Full Text] [PDF]

				K. M. Schmidt-Ott, J. Yang, X. Chen, H. Wang, N. Paragas, K. Mori, J.-Y. Li, B. Lu, F. Costantini, M. Schiffer, et al. Novel Regulators of Kidney Development from the Tips of the Ureteric Bud J. Am. Soc. Nephrol., July 1, 2005; 16(7): 1993 - 2002. [Abstract] [Full Text] [PDF]

				A. Kobayashi, K.-M. Kwan, T. J. Carroll, A. P. McMahon, C. L. Mendelsohn, and R. R. Behringer Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development Development, June 15, 2005; 132(12): 2809 - 2823. [Abstract] [Full Text] [PDF]

				A. C. Jung, B. Denholm, H. Skaer, and M. Affolter Renal Tubule Development in Drosophila: A Closer Look at the Cellular Level J. Am. Soc. Nephrol., February 1, 2005; 16(2): 322 - 328. [Abstract] [Full Text] [PDF]

				R. V. Sampogna and S. K. Nigam Implications of Gene Networks for Understanding Resilience and Vulnerability in the Kidney Branching Program Physiology, December 1, 2004; 19(6): 339 - 347. [Abstract] [Full Text] [PDF]

				A. Karihaloo, S. Kale, N. D. Rosenblum, and L. G. Cantley Hepatocyte Growth Factor-Mediated Renal Epithelial Branching Morphogenesis Is Regulated by Glypican-4 Expression Mol. Cell. Biol., October 1, 2004; 24(19): 8745 - 8752. [Abstract] [Full Text] [PDF]