|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
First published online 5 January 2005
doi: 10.1242/dev.01600
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4
7UH, UK
2 Business Unit Bioscience, Plant Research International, PO Box 16, 6700 AA
Wageningen, The Netherlands
* Author for correspondence (e-mail: robert.sablowski{at}bbsrc.ac.uk)
Accepted 25 November 2004
Floral organs, whose identity is determined by specific combinations of homeotic genes, originate from a group of undifferentiated cells called the floral meristem. In Arabidopsis, the homeotic gene AGAMOUS (AG) terminates meristem activity and promotes development of stamens and carpels. To understand the program of gene expression activated by AG, we followed genome-wide expression during early stamen and carpel development. The AG target genes included most genes for which mutant screens revealed a function downstream of AG. Novel targets were validated by in situ hybridisation and binding to AG in vitro and in vivo. Transcription factors formed a large fraction of AG targets, suggesting that during early organogenesis, much of the genetic program is concerned with elaborating gene expression patterns. The results also suggest that AG and other homeotic proteins with which it interacts (SEPALLATA3, APETALA3, PISTILLATA) are coordinately regulated in a positive-feedback loop to maintain their own expression, and that AG activates biosynthesis of gibberellin, which has been proposed to promote the shift from meristem identity to differentiation.
Key words: Homeotic genes, Floral development, Transcription, AGAMOUS
This article has been cited by other articles:
|
|
 |
|
  C. Gomez-Mena and R. Sablowski ARABIDOPSIS THALIANA HOMEOBOX GENE1 Establishes the Basal Boundaries of Shoot Organs and Controls Stem Growth PLANT CELL, August 1, 2008; 20(8): 2059 - 2072. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. Castellano and R. Sablowski Phosducin-Like Protein 3 Is Required for Microtubule-Dependent Steps of Cell Division but Not for Meristem Growth in Arabidopsis PLANT CELL, April 1, 2008; 20(4): 969 - 981. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Prunet, P. Morel, A.-M. Thierry, Y. Eshed, J. L. Bowman, I. Negrutiu, and C. Trehin REBELOTE, SQUINT, and ULTRAPETALA1 Function Redundantly in the Temporal Regulation of Floral Meristem Termination in Arabidopsis thaliana PLANT CELL, April 1, 2008; 20(4): 901 - 919. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Hu, M. G. Mitchum, N. Barnaby, B. T. Ayele, M. Ogawa, E. Nam, W.-C. Lai, A. Hanada, J. M. Alonso, J. R. Ecker, et al. Potential Sites of Bioactive Gibberellin Production during Reproductive Growth in Arabidopsis PLANT CELL, February 1, 2008; 20(2): 320 - 336. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Ito, K.-H. Ng, T.-S. Lim, H. Yu, and E. M. Meyerowitz The Homeotic Protein AGAMOUS Controls Late Stamen Development by Regulating a Jasmonate Biosynthetic Gene in Arabidopsis PLANT CELL, November 1, 2007; 19(11): 3516 - 3529. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Alves-Ferreira, F. Wellmer, A. Banhara, V. Kumar, J. L. Riechmann, and E. M. Meyerowitz Global Expression Profiling Applied to the Analysis of Arabidopsis Stamen Development Plant Physiology, November 1, 2007; 145(3): 747 - 762. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Theissen and R. Melzer Molecular Mechanisms Underlying Origin and Diversification of the Angiosperm Flower Ann. Bot., September 1, 2007; 100(3): 603 - 619. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Sablowski Flowering and determinacy in Arabidopsis J. Exp. Bot., March 1, 2007; 58(5): 899 - 907. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ciannamea, K. Kaufmann, M. Frau, I. A. N. Tonaco, K. Petersen, K. K. Nielsen, G. C. Angenent, and R. G. H. Immink Protein interactions of MADS box transcription factors involved in flowering in Lolium perenne J. Exp. Bot., October 1, 2006; 57(13): 3419 - 3431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Teeri, A. Uimari, M. Kotilainen, R. Laitinen, H. Help, P. Elomaa, and V. A. Albert Reproductive meristem fates in Gerbera J. Exp. Bot., October 1, 2006; 57(13): 3445 - 3455. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Brady, T. A. Long, and P. N. Benfey Unraveling the dynamic transcriptome. PLANT CELL, September 1, 2006; 18(9): 2101 - 2111. [Full Text] [PDF]
|
|
|
|
 |
|
 V. V. Sridhar, A. Surendrarao, and Z. Liu APETALA1 and SEPALLATA3 interact with SEUSS to mediate transcription repression during flower development Development, August 15, 2006; 133(16): 3159 - 3166. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Rijpkema, S. Royaert, J. Zethof, G. van der Weerden, T. Gerats, and M. Vandenbussche Analysis of the Petunia TM6 MADS Box Gene Reveals Functional Divergence within the DEF/AP3 Lineage PLANT CELL, August 1, 2006; 18(8): 1819 - 1832. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. P. Scutt, M. Vinauger-Douard, C. Fourquin, C. Finet, and C. Dumas An evolutionary perspective on the regulation of carpel development J. Exp. Bot., July 1, 2006; 57(10): 2143 - 2152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Gregis, A. Sessa, L. Colombo, and M. M. Kater AGL24, SHORT VEGETATIVE PHASE, and APETALA1 Redundantly Control AGAMOUS during Early Stages of Flower Development in Arabidopsis PLANT CELL, June 1, 2006; 18(6): 1373 - 1382. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Palaniswamy, S. James, H. Sun, R. S. Lamb, R. V. Davuluri, and E. Grotewold AGRIS and AtRegNet. A Platform to Link cis-Regulatory Elements and Transcription Factors into Regulatory Networks Plant Physiology, March 1, 2006; 140(3): 818 - 829. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ferrario, A. V. Shchennikova, J. Franken, R. G.H. Immink, and G. C. Angenent Control of Floral Meristem Determinacy in Petunia by MADS-Box Transcription Factors Plant Physiology, March 1, 2006; 140(3): 890 - 898. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. B. Bajic, M. Veronika, P. S. Veladandi, A. Meka, M.-W. Heng, K. Rajaraman, H. Pan, and S. Swarup Dragon Plant Biology Explorer. A Text-Mining Tool for Integrating Associations between Genetic and Biochemical Entities with Genome Annotation and Biochemical Terms Lists Plant Physiology, August 1, 2005; 138(4): 1914 - 1925. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. de Folter, R. G.H. Immink, M. Kieffer, L. Parenicova, S. R. Henz, D. Weigel, M. Busscher, M. Kooiker, L. Colombo, M. M. Kater, et al. Comprehensive Interaction Map of the Arabidopsis MADS Box Transcription Factors PLANT CELL, May 1, 2005; 17(5): 1424 - 1433. [Abstract] [Full Text] [PDF]
|
|
