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Fig. 3. Overlapping expression of Pdgfra, Sox10, Olig1, Olig2 and Shh in the ventral forebrain and neocortex. (A-E) Serial coronal sections of rat E14.5 forebrain. The four presumptive oligodendrocyte lineage markers show overlapping but non-identical patterns of expression in the neuroepithelium, SVZ and mantle zones of the anterior hypothalamus and MGE. Their expression domains also overlap Shh expression in the neuroepithelium (E). The neuroepithelial expression of Olig2 extends further than the rest, through the MGE and LGE (D). (F) Diagram to indicate the approximate position of sections A-E. (G-K) Serial coronal sections through the rat cortex at E18.5. Cells expressing Pdgfra, Sox10, Olig1 and Olig2 have a similar scattered distribution in the cortex at this stage. Shh cannot be detected in the cortex (K). The position of sections G-K is indicated in L. Cx, cortex; Th, thalamus; Hy, hypothalamus; BG, basal ganglia.





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