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Fig. 7. DAC regulates the progressive expression of DL and fringe. (A-C) DL expression (red) occurs progressively with more rings of expression added as development proceeds. (D) DL (red) and SER (green) expression are coincident within the coxa of early third instar leg discs (arrow). (E,F) ptcGAL4 UASdac UASGFP early third instar leg disc. DL expression is cell autonomously induced by DAC (arrow). (G) fringe expression at early third instar. Expression is visible in a single proximal ring (arrow). (H) fringe expression at early-mid third instar. Expression is observed in three rings and a central spot. (I) ptcGAL4 UASdac expression results in the induction of fringe expression in a stripe along the AP axis of the developing leg (arrow).





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