Fig. 1. Reduction of fet function produces a dorsalized maternal effect phenotype and zygotic wing defect. (A,B) Eggshell produced by wild-type and fetU6/fetE11 female (dorsal view). The fet egg is shorter than wild type, with broader dorsal appendages that are shifted laterally and appendage base material encircling the anterior circumference. In all panels depicting an eggshell or embryo, anterior is towards the left. (C,D) Cuticle of embryo produced by wild-type and fetU6/fetE11 female. The fet embryo is dorsalized, and lacks ventral and lateral denticle bands. (E,F) Expression of zen RNA in blastoderm embryo produced by wild-type and fetT6/fetE11 female (lateral view, dorsal side upwards). The domain of this dorsal marker is expanded along the entire DV axis in the fet embryo. (G,H) Expression of sog RNA in blastoderm embryo produced by wild-type and fetT6/fetE11 female. In this lateral view, only one of the two stripes expressed in the wild-type embryo is visible. No sog RNA is detected in the fet embryo except for a posterior spot. (I,J) Expression of Twist protein in blastoderm embryo produced by wild-type and fetT6/fetE11 female. This ventral marker is not detected in the fet embryo, except for expression at the termini, which is regulated independently of the DV pathway. (K,L) Wing blade of wild-type and fetU6/fetE11 fly. The fet wing is smaller than wild-type, and exhibits vein thickening and blistering.
