Fig. 6. string-lacZ reporter expression is regulated by the Snail protein family. RNA in situ hybridization using an antisense lacZ probe reveals string promoter-lacZ reporter expression. Two different string-lacZ reporters were used. (A-F) Embryos expressing string 5.3-lacZ. (G-L) embryos expressing string 6.4-lacZ. (A,B,G,H) Wild-type embryos. (C,I,J) osp29 embryos. (D) Another deletion do-1 embryo (Ashraf et al., 1999). (E,F,K,L) osp29 embryos carrying the indicated rescue transgenes. In the deletion mutants, the lacZ expression is almost abolished. A single copy of each of the indicated transgenes was sufficient to confer a clear rescue of the reporter expression.
